|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human CDK5 ORF mammalian expression plasmid, C-GFPSpark tag||HG10897-ACG|
|Human CDK5 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10897-ACR|
|Human CDK5 ORF mammalian expression plasmid, N-GFPSpark tag||HG10897-ANG|
|Human CDK5 ORF mammalian expression plasmid, N-OFPSpark / RFP tag||HG10897-ANR|
|Human CDK5 ORF mammalian expression plasmid, C-Flag tag||HG10897-CF|
|Human CDK5 ORF mammalian expression plasmid, C-His tag||HG10897-CH|
|Human CDK5 ORF mammalian expression plasmid, C-Myc tag||HG10897-CM|
|Human CDK5 ORF mammalian expression plasmid, C-HA tag||HG10897-CY|
|Human CDK5 Gene cDNA clone plasmid||HG10897-M|
|Human CDK5 natural ORF mammalian expression plasmid||HG10897-M-N|
|Human CDK5 ORF mammalian expression plasmid, N-Flag tag||HG10897-NF|
|Human CDK5 ORF mammalian expression plasmid, N-His tag||HG10897-NH|
|Human CDK5 ORF mammalian expression plasmid, N-Myc tag||HG10897-NM|
|Human CDK5 ORF mammalian expression plasmid, N-HA tag||HG10897-NY|
|Human CDK5 natural ORF mammalian expression plasmid||HG10897-UT|
|Learn more about expression Vectors|
Cell division protein kinase 5, also known as Cyclin-dependent kinase 5, Serine/threonine-protein kinase PSSALRE, Tau protein kinase II catalytic subunit, TPKII catalytic subunit and CDK5, is a cytoplasm protein which belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and CDC2 / CDKX subfamily. Cyclin-dependent kinases (Cdks) are a family of proline-directed Ser/Thr kinases known for their role in the control of cell cycle progression. In 1992, this family was joined by CDK5, which is an atypical member in that it uses its own activators and is multifunctional, playing important regulatory roles in multiple cellular functions. CDK5, unlike other Cdks, is not regulated by cyclins, and its activity is primarily detected in postmitotic neurons in developing and adult nervous systems. CDK5 is activated by association with a neuron-specific activator, p35 or its isoform p39. CDK5 is probably involved in the control of the cell cycle. It interacts with D1 and D3-type G1 cyclins. CDK5 can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. It also interacts with p35 which activates the kinase. CDK5 plays important roles in various neuronal activities, including neuronal migration, synaptic activity, and neuronal cell death.