|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human IL17R ORF mammalian expression plasmid, C-GFPSpark tag||HG10895-ACG|
|Human IL17R ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10895-ACR|
|Human IL17R ORF mammalian expression plasmid, C-Flag tag||HG10895-CF|
|Human IL17R ORF mammalian expression plasmid, C-His tag||HG10895-CH|
|Human IL17R ORF mammalian expression plasmid, C-Myc tag||HG10895-CM|
|Human IL17R ORF mammalian expression plasmid, C-HA tag||HG10895-CY|
|Human IL17R Gene cDNA clone plasmid||HG10895-M|
|Human IL17R ORF mammalian expression plasmid, N-Flag tag||HG10895-NF|
|Human IL17R ORF mammalian expression plasmid, N-His tag||HG10895-NH|
|Human IL17R ORF mammalian expression plasmid, N-Myc tag||HG10895-NM|
|Human IL17R ORF mammalian expression plasmid, N-HA tag||HG10895-NY|
|Human IL17R natural ORF mammalian expression plasmid||HG10895-UT|
|Learn more about expression Vectors|
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor which binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R/IL-17RA (CD217) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor IL-17RA play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Defects in IL-17R/IL-17RA (CD217) are the cause of familial candidiasis type 5 (CANDF5). CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.