|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.
|Human BCHE ORF mammalian expression plasmid, C-GFPSpark tag||HG12010-ACG|
|Human BCHE ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG12010-ACR|
|Human BCHE ORF mammalian expression plasmid, C-Flag tag||HG12010-CF|
|Human BCHE ORF mammalian expression plasmid, C-His tag||HG12010-CH|
|Human BCHE ORF mammalian expression plasmid, C-Myc tag||HG12010-CM|
|Human BCHE ORF mammalian expression plasmid, C-HA tag||HG12010-CY|
|Human BCHE Gene cDNA clone plasmid||HG12010-G|
|Human BCHE ORF mammalian expression plasmid, Flag tag||HG12010-G-F|
|Human BCHE ORF mammalian expression plasmid, N-Flag tag||HG12010-NF|
|Human BCHE ORF mammalian expression plasmid, N-His tag||HG12010-NH|
|Human BCHE ORF mammalian expression plasmid, N-Myc tag||HG12010-NM|
|Human BCHE ORF mammalian expression plasmid, N-HA tag||HG12010-NY|
|Human BCHE natural ORF mammalian expression plasmid||HG12010-UT|
|Learn more about expression Vectors|
Butyrylcholinesterase (BCHE), also known as cholinesterase or BuChE, is an enzyme defined as "pseudo" or "non-neuronal" cholinesterase. Butyrylcholinesterase (BCHE) is widely distributed in the nervous system as well as blood plasma. It is constitutively similar to the neuronal acetylcholinesterase, and is a non-specific cholinesterase which hydrolyses many different choline esters. Butyrylcholinesterase (BCHE) is a glycoprotein of 4 identical subunits, that were arranged as a dimer of dimers with each dimer composed of two identical subunits joined by interchain disulfide bonds. Butyrylcholinesterase (BCHE) behaves principally similar to the true enzyme and thus can play a similar role in nerve conduction, although it participates probably only in relatively slow conductive processes and could be involved in other nervous system functions and in neurodegenerative diseases. It can hydrolyze toxic esters such as cocaine or scavenge organophosphorus pesticides and nerve agents. Purified human serum cholinesterase combines in its active surface an anionic and an esteratic site, similar to true cholinesterase. It has been demonstrated that butyrylcholinesterase (BCHE) may have a greater role in cholinergic transmission than previously surmised, making BChE inhibition an important therapeutic goal in Alzheimer's disease.