|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human OMD ORF mammalian expression plasmid, C-GFPSpark tag||HG10825-ACG|
|Human OMD ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10825-ACR|
|Human OMD ORF mammalian expression plasmid, C-Flag tag||HG10825-CF|
|Human OMD ORF mammalian expression plasmid, C-His tag||HG10825-CH|
|Human OMD ORF mammalian expression plasmid, C-Myc tag||HG10825-CM|
|Human OMD ORF mammalian expression plasmid, C-HA tag||HG10825-CY|
|Human OMD Gene cDNA clone plasmid||HG10825-M|
|Human OMD ORF mammalian expression plasmid, Flag tag||HG10825-M-F|
|Human OMD ORF mammalian expression plasmid, N-Flag tag||HG10825-NF|
|Human OMD ORF mammalian expression plasmid, N-His tag||HG10825-NH|
|Human OMD ORF mammalian expression plasmid, N-Myc tag||HG10825-NM|
|Human OMD ORF mammalian expression plasmid, N-HA tag||HG10825-NY|
|Human OMD natural ORF mammalian expression plasmid||HG10825-UT|
|Learn more about expression Vectors|
Osteomodulin (OMD), also known as Osteoadherin (OSAD), Keratan sulfate proteoglycan osteomodulin, KSPG osteomodulin, and SLRR2C, is a secreted protein which belongs to the small leucine-rich proteoglycan (SLRP) family and Class II subfamily. SLRP family proteins are normally found in extracellular matrices, but Osteomodulin is the only member restricted to mineralized tissues. Osteomodulin is primarily expressed by osteoblasts and might have a role in regulation of mineralization. In bone OSAD has been localized in primary spongiosa within the bovine fetal rib growth plate. Moreover, in situ hybridization has shown expression of OSAD in osteoblasts close to the cartilage and bone border in the growth plate of rat femur. OSAD may play an important role during tooth development and biomineralization of dentin. Osteomodulin is a cell binding keratan sulfate proteoglycan which was recently isolated from mineralized bovine bone and subsequently cloned and sequenced. Osteomodulin may be implicated in biomineralization processes. It has a function in binding of osteoblasts via the alpha (V) beta (3)-integrin. It is likely that Osteomodulin is an osteoblast maturation marker that is induced by osteoclast activity. Osteomodulin is also an early marker for terminally differentiated matrix producing osteoblasts.