|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human CXADR ORF mammalian expression plasmid, C-GFPSpark tag||HG10799-ACG|
|Human CXADR ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10799-ACR|
|Human CXADR ORF mammalian expression plasmid, C-Flag tag||HG10799-CF|
|Human CXADR ORF mammalian expression plasmid, C-His tag||HG10799-CH|
|Human CXADR ORF mammalian expression plasmid, C-Myc tag||HG10799-CM|
|Human CXADR ORF mammalian expression plasmid, C-HA tag||HG10799-CY|
|Human CXADR Gene cDNA clone plasmid||HG10799-M|
|Human CXADR ORF mammalian expression plasmid, N-Flag tag||HG10799-NF|
|Human CXADR ORF mammalian expression plasmid, N-His tag||HG10799-NH|
|Human CXADR ORF mammalian expression plasmid, N-Myc tag||HG10799-NM|
|Human CXADR ORF mammalian expression plasmid, N-HA tag||HG10799-NY|
|Human CXADR natural ORF mammalian expression plasmid||HG10799-UT|
|Learn more about expression Vectors|
CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 107 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 90% sequence identity with the corresponding regions of rat, human CXADR.