|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human TGFBR3 ORF mammalian expression plasmid, C-GFPSpark tag||HG10778-ACG|
|Human TGFBR3 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10778-ACR|
|Human TGFBR3 ORF mammalian expression plasmid, C-Flag tag||HG10778-CF|
|Human TGFBR3 ORF mammalian expression plasmid, C-His tag||HG10778-CH|
|Human TGFBR3 ORF mammalian expression plasmid, C-Myc tag||HG10778-CM|
|Human TGFBR3 ORF mammalian expression plasmid, C-HA tag||HG10778-CY|
|Human TGFBR3 Gene cDNA clone plasmid||HG10778-M|
|Human TGFBR3 natural ORF mammalian expression plasmid||HG10778-M-N|
|Human TGFBR3 ORF mammalian expression plasmid, N-Flag tag||HG10778-NF|
|Human TGFBR3 ORF mammalian expression plasmid, N-His tag||HG10778-NH|
|Human TGFBR3 ORF mammalian expression plasmid, N-Myc tag||HG10778-NM|
|Human TGFBR3 ORF mammalian expression plasmid, N-HA tag||HG10778-NY|
|Human TGFBR3 natural ORF mammalian expression plasmid||HG10778-UT|
|Learn more about expression Vectors|
Betaglycan also known as transforming growth factor beta receptor III (TGFBR3), is a cell-surface chondroitin sulfate / heparan sulfate proteoglycan. TGFBR3 is a transforming growth factor (TGF)-beta type III receptor. This receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. TGFBR3 is the TGF-β component most commonly downregulated among localized human prostate cancer studies. TGFBR3 knockdown led to focus formation and enhanced expression of CD133, a marker found on prostate cancer stem cells. TGFBR3 is an accessory receptor that binds to and modulates the activities of both transforming growth factor-beta (TGFβ) and inhibin, two members of the TGFβ superfamily of growth factors that regulate many aspects of reproductive biology. TGFBR3 is known to be expressed in adult testis and ovary, but little is known about this receptor during gonadogenesis.