|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human DPP-II ORF mammalian expression plasmid, C-GFPSpark tag||HG10748-ACG|
|Human DPP-II ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10748-ACR|
|Human DPP-II ORF mammalian expression plasmid, C-Flag tag||HG10748-CF|
|Human DPP-II ORF mammalian expression plasmid, C-His tag||HG10748-CH|
|Human DPP-II ORF mammalian expression plasmid, C-Myc tag||HG10748-CM|
|Human DPP-II ORF mammalian expression plasmid, C-HA tag||HG10748-CY|
|Human DPP-II Gene cDNA clone plasmid||HG10748-M|
|Human DPP-II ORF mammalian expression plasmid, N-Flag tag||HG10748-NF|
|Human DPP-II ORF mammalian expression plasmid, N-His tag||HG10748-NH|
|Human DPP-II ORF mammalian expression plasmid, N-Myc tag||HG10748-NM|
|Human DPP-II ORF mammalian expression plasmid, N-HA tag||HG10748-NY|
|Human DPP-II natural ORF mammalian expression plasmid||HG10748-UT|
|Learn more about expression Vectors|
DPP7 (dipeptidylpeptidase 7), also known as DPPII and DPP2, is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. Dipeptidyl peptidases (DPPs) have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. It localizes to lysosomes. DPP7 localizes to lysosomes and exists as a homodimer via its leucine zipper motif and is involved in the degradation of oligopeptides. In response to calcium release, it can be secreted in its active form. It is essential for lymphocyte survival, as the inhibition of DPP7 results in quiescent cell apoptosis.