|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human JAM-B ORF mammalian expression plasmid, C-GFPSpark tag||HG10580-ACG|
|Human JAM-B ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10580-ACR|
|Human JAM-B ORF mammalian expression plasmid, C-Flag tag||HG10580-CF|
|Human JAM-B ORF mammalian expression plasmid, C-His tag||HG10580-CH|
|Human JAM-B ORF mammalian expression plasmid, C-Myc tag||HG10580-CM|
|Human JAM-B ORF mammalian expression plasmid, C-HA tag||HG10580-CY|
|Human JAM-B Gene cDNA clone plasmid||HG10580-M|
|Human JAM-B ORF mammalian expression plasmid, Flag tag||HG10580-M-F|
|Human JAM-B ORF mammalian expression plasmid, N-Flag tag||HG10580-NF|
|Human JAM-B ORF mammalian expression plasmid, N-His tag||HG10580-NH|
|Human JAM-B ORF mammalian expression plasmid, N-Myc tag||HG10580-NM|
|Human JAM-B ORF mammalian expression plasmid, N-HA tag||HG10580-NY|
|Human JAM-B natural ORF mammalian expression plasmid||HG10580-UT|
|Learn more about expression Vectors|
Junctional adhesion molecule B (JAM-B), also known as Junctional adhesion molecule 2 (JAM2), Vascular endothelial junction-associated molecule (VE-JAM), and CD322, is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily. It is prominently expressed on high endothelial venules. expression to be restricted to the high endothelial venule of tonsil and lymph nodes. The localization to the endothelium of arterioles in and around inflammatory and tumor foci. JAM-B can function as an adhesive ligand for the T cell line J45 and can interact with GM-CSF/IL-4-derived peripheral blood dendritic cells, circulating CD56(+) NK cells, circulating CD56(+)CD3(+) NK/T cells, and circulating CD56(+)CD3(+)CD8(+) cytolytic T cells. JAM-2 is expressed on high endothelial venules (HEVs) in human tonsil and on a subset of human leukocytes, suggesting that JAM-2 plays a central role in the regulation of transendothelial migration. It binds to very late activation antigen (VLA)-4, a leucocyte integrin that contributes to rolling and firm adhesion of lymphocytes to endothelial cells through binding to vascular cell adhesion molecule (VCAM)-1. JAM-B appears to contribute to leucocyte extravasation by facilitating not only transmigration but also rolling and adhesion. JAM-B acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.