|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human IL2Rg ORF mammalian expression plasmid, C-GFPSpark tag||HG10555-ACG|
|Human IL2Rg ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10555-ACR|
|Human IL2Rg ORF mammalian expression plasmid, C-Flag tag||HG10555-CF|
|Human IL2Rg ORF mammalian expression plasmid, C-His tag||HG10555-CH|
|Human IL2Rg ORF mammalian expression plasmid, C-Myc tag||HG10555-CM|
|Human IL2Rg ORF mammalian expression plasmid, C-HA tag||HG10555-CY|
|Human IL2Rg Gene cDNA clone plasmid||HG10555-M|
|Human IL2Rg ORF mammalian expression plasmid, N-Flag tag||HG10555-NF|
|Human IL2Rg ORF mammalian expression plasmid, N-His tag||HG10555-NH|
|Human IL2Rg ORF mammalian expression plasmid, N-Myc tag||HG10555-NM|
|Human IL2Rg ORF mammalian expression plasmid, N-HA tag||HG10555-NY|
|Human IL2Rg natural ORF mammalian expression plasmid||HG10555-UT|
|Learn more about expression Vectors|
The common gamma chain (γc) (or CD132), also known as interleukin-2 receptor subunit gamma or IL2RG, is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. The common gamma chain (γc) (or IL2RG), is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors: IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin-21 receptor. It is a component of multiple cytokine receptors that are essential for lymphocyte development and function. X-linked severe combined immunodeficiency (XSCID) is a rare and potentially fatal disease caused by mutations of IL2RG, the gene encoding IL2RG. IL2RG was demonstrated to be a component of the IL-4 receptor on the basis of chemical cross-linking data, the ability of IL2RG to augment IL-4 binding affinity. The observation that IL-2R gamma is a functional component of the IL-4 receptor, together with the finding that IL-2R gamma associates with the IL-7 receptor, begins to elucidate why deficiency of this common gamma chain (gamma c) has a profound effect on lymphoid function and development, as seen in X-linked severe combined immunodeficiency.