|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rhesus SIRPG ORF mammalian expression plasmid, C-GFPSpark tag||CG90226-ACG|
|Rhesus SIRPG ORF mammalian expression plasmid, C-OFPSpark / RFP tag||CG90226-ACR|
|Rhesus SIRPG ORF mammalian expression plasmid, C-Flag tag||CG90226-CF|
|Rhesus SIRPG ORF mammalian expression plasmid, C-His tag||CG90226-CH|
|Rhesus SIRPG ORF mammalian expression plasmid, C-Myc tag||CG90226-CM|
|Rhesus SIRPG ORF mammalian expression plasmid, C-HA tag||CG90226-CY|
|Rhesus SIRPG Gene cDNA clone plasmid||CG90226-G|
|Rhesus SIRPG ORF mammalian expression plasmid, N-Flag tag||CG90226-NF|
|Rhesus SIRPG ORF mammalian expression plasmid, N-His tag||CG90226-NH|
|Rhesus SIRPG ORF mammalian expression plasmid, N-Myc tag||CG90226-NM|
|Rhesus SIRPG ORF mammalian expression plasmid, N-HA tag||CG90226-NY|
|Rhesus SIRPG natural ORF mammalian expression plasmid||CG90226-UT|
|Learn more about expression Vectors|
Signal-regulatory protein gamma (SIRPG/SIRP gamma) also known as CD172 antigen-like family member B, CD172g, and CD172g antigen, is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. SIRPG/SIRP gamma/CD172g is probable immunoglobulin-like cell surface receptor. On binding with CD47, SIRPG can mediate cell-cell adhesion. SIRPG/SIRP gamma is engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRPG/SIRP gamma/CD172g is detected in liver, and at very low levels in brain, heart, lung, pancreas, kidney, placenta and skeletal muscle. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. This cytokine is mainly present in the paracortical T-cell area of lymph nodes, with only sparse positive cells in the mantle and in the germinal center of B-cell follicles. In the thymus, SIRPG is primarily expressed in the medulla on mature T-lymphocytes that have undergone thymic selection.