|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rhesus CD84 ORF mammalian expression plasmid, C-GFPSpark tag||CG90203-ACG|
|Rhesus CD84 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||CG90203-ACR|
|Rhesus CD84 ORF mammalian expression plasmid, C-Flag tag||CG90203-CF|
|Rhesus CD84 ORF mammalian expression plasmid, C-His tag||CG90203-CH|
|Rhesus CD84 ORF mammalian expression plasmid, C-Myc tag||CG90203-CM|
|Rhesus CD84 ORF mammalian expression plasmid, C-HA tag||CG90203-CY|
|Rhesus CD84 Gene cDNA clone plasmid||CG90203-G|
|Rhesus CD84 ORF mammalian expression plasmid, N-Flag tag||CG90203-NF|
|Rhesus CD84 ORF mammalian expression plasmid, N-His tag||CG90203-NH|
|Rhesus CD84 ORF mammalian expression plasmid, N-Myc tag||CG90203-NM|
|Rhesus CD84 ORF mammalian expression plasmid, N-HA tag||CG90203-NY|
|Rhesus CD84 natural ORF mammalian expression plasmid||CG90203-UT|
|Learn more about expression Vectors|
The CD2 family receptors are type I transmembrane glycoproteins belonging to immunoglobulin (Ig) superfamily characterized by a membrane-proximal Ig constant 2 (C2) domain and a membrane-distal variable (V) domain that is responsible for ligand recognition. CD84, also known as LY9B and SLAMF5, is a homophilic member of the SLAM (signaling lymphocyte activation molecule) subfamily of the CD2 family. The SLAM family receptorsmediate signal transduction through the interaction of its ITSM (immunoreceptor tyrosine-based switch motifs) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. The CD84-CD84 interaction was independent of its cytoplasmic tail. Thus, CD84 is its own ligand and acts as a costimulatory molecule. CD84 is expressed on cells from almost all hematopoietic lineages and on CD34+ hematopoietic progenitor cells, suggesting that CD84 serves as a marker for committed hematopoietic progenitor cells.