|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human BMP-7 ORF mammalian expression plasmid, C-GFPSpark tag||HG10083-ACG|
|Human BMP-7 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10083-ACR|
|Human BMP-7 ORF mammalian expression plasmid, C-Flag tag||HG10083-CF|
|Human BMP-7 ORF mammalian expression plasmid, C-His tag||HG10083-CH|
|Human BMP-7 ORF mammalian expression plasmid, C-Myc tag||HG10083-CM|
|Human BMP-7 ORF mammalian expression plasmid, C-HA tag||HG10083-CY|
|Human BMP-7 Gene cDNA clone plasmid||HG10083-M|
|Human BMP-7 natural ORF mammalian expression plasmid, HA tag||HG10083-M-Y|
|Human BMP-7 ORF mammalian expression plasmid, N-Flag tag||HG10083-NF|
|Human BMP-7 ORF mammalian expression plasmid, N-His tag||HG10083-NH|
|Human BMP-7 ORF mammalian expression plasmid, N-Myc tag||HG10083-NM|
|Human BMP-7 ORF mammalian expression plasmid, N-HA tag||HG10083-NY|
|Human BMP-7 natural ORF mammalian expression plasmid||HG10083-UT|
|Learn more about expression Vectors|
BMP-7 (Bone morphogenetic protein 7), also known as osteogenic protein 1 (OP-1), is a bone morphogenetic protein which belongs to the TGF-β superfamily. OP-1 is expressed in the brain, kidneys and bladder. BMP-7 may be involved in bone homeostasis. Osteogenic protein 1 plays a key role in the transformation of mesenchymal cells into bone and cartilage. The phosphorylation of SMAD1 and SMAD5 can be induced by BMP-7, which in turn induce transcription of numerous osteogenic genes. BMP-7 treatment can also induce all of the genetic markers of osteoblast differentiation in many cell types. The expression of BMP-7 causes ventral phenotypes while its complete inhibition creates a dorsal phenotype. Human recombinant BMP-7 protein can be used to aid in the fusion of vertebral bodies to prevent neurologic trauma. It also functions in the treatment of tibial non-union, frequently in cases where a bone graft has failed. It is found that BMP7 has the potential for treatment of chronic kidney disease.