|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.
|Human CD38 ORF mammalian expression plasmid, C-GFPSpark tag||HG10818-ACG|
|Human CD38 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10818-ACR|
|Human CD38 ORF mammalian expression plasmid, C-Flag tag||HG10818-CF|
|Human CD38 ORF mammalian expression plasmid, C-His tag||HG10818-CH|
|Human CD38 ORF mammalian expression plasmid, C-Myc tag||HG10818-CM|
|Human CD38 ORF mammalian expression plasmid, C-HA tag||HG10818-CY|
|Human CD38 Gene cDNA clone plasmid||HG10818-M|
|Human CD38 ORF mammalian expression plasmid, N-Flag tag||HG10818-NF|
|Human CD38 ORF mammalian expression plasmid, N-His tag||HG10818-NH|
|Human CD38 ORF mammalian expression plasmid, N-Myc tag||HG10818-NM|
|Human CD38 ORF mammalian expression plasmid, N-HA tag||HG10818-NY|
|Human CD38 natural ORF mammalian expression plasmid||HG10818-UT|
|Learn more about expression Vectors|
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.