|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Ferret CD74 ORF mammalian expression plasmid, C-GFPSpark tag||FG60049-ACG|
|Ferret CD74 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||FG60049-ACR|
|Ferret CD74 ORF mammalian expression plasmid, C-Flag tag||FG60049-CF|
|Ferret CD74 ORF mammalian expression plasmid, C-His tag||FG60049-CH|
|Ferret CD74 ORF mammalian expression plasmid, C-Myc tag||FG60049-CM|
|Ferret CD74 ORF mammalian expression plasmid, C-HA tag||FG60049-CY|
|Ferret CD74 Gene cDNA clone plasmid||FG60049-G|
|Ferret CD74 ORF mammalian expression plasmid, N-Flag tag||FG60049-NF|
|Ferret CD74 ORF mammalian expression plasmid, N-His tag||FG60049-NH|
|Ferret CD74 ORF mammalian expression plasmid, N-Myc tag||FG60049-NM|
|Ferret CD74 ORF mammalian expression plasmid, N-HA tag||FG60049-NY|
|Ferret CD74 natural ORF mammalian expression plasmid||FG60049-UT|
|Learn more about expression Vectors|
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD74, also known as HLA class2 histocompatibility antigen gamma chain and HLA-DR antigens-associated invariant chain, is a polypeptide involved in the formation and transport of MHC class2 protein. CD74 is expressed by B cells, macrophages, and Reed-Sternberg cells. When MHC class 2 protein was in the rough ER, its peptide-binding cleft was blocked by CD74 to prevent it from interacting with the endogenous peptides. CD74 also serves to facilitate MHC class2's export from ER.