|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Canine EFNB2 ORF mammalian expression plasmid, C-GFPSpark tag||DG70073-ACG|
|Canine EFNB2 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||DG70073-ACR|
|Canine EFNB2 ORF mammalian expression plasmid, C-Flag tag||DG70073-CF|
|Canine EFNB2 ORF mammalian expression plasmid, C-His tag||DG70073-CH|
|Canine EFNB2 ORF mammalian expression plasmid, C-Myc tag||DG70073-CM|
|Canine EFNB2 ORF mammalian expression plasmid, C-HA tag||DG70073-CY|
|Canine EFNB2 Gene cDNA clone plasmid||DG70073-G|
|Canine EFNB2 ORF mammalian expression plasmid, N-Flag tag||DG70073-NF|
|Canine EFNB2 ORF mammalian expression plasmid, N-His tag||DG70073-NH|
|Canine EFNB2 ORF mammalian expression plasmid, N-Myc tag||DG70073-NM|
|Canine EFNB2 ORF mammalian expression plasmid, N-HA tag||DG70073-NY|
|Canine EFNB2 natural ORF mammalian expression plasmid||DG70073-UT|
|Learn more about expression Vectors|
EphrinB2 also known as EFNB2 is a member of the ephrin family. EphrinB2 is involved in establishing arterial versus venous identity and perhaps in anastamosing arterial and venous vessels at their junctions. The transmembrane-associated ephrin ligands and their Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Eph/ephrin interactions are implicated in axon guidance, neural crest cell migration, establishment of segmental boundaries, and formation of angiogenic capillary plexi. Eph receptors and ephrins are divided into two subclasses, A and B, based on binding specificities. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. EphrinB2 expression progressively extends from the arterial endothelium to surrounding smooth muscle cells and to pericytes, suggesting that ephrin-B2 may play an important role during formation of the arterial muscle wall.