|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.
|Human FGF10 ORF mammalian expression plasmid, C-GFPSpark tag||HG10573-ACG|
|Human FGF10 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10573-ACR|
|Human FGF10 ORF mammalian expression plasmid, C-Flag tag||HG10573-CF|
|Human FGF10 ORF mammalian expression plasmid, C-His tag||HG10573-CH|
|Human FGF10 ORF mammalian expression plasmid, C-Myc tag||HG10573-CM|
|Human FGF10 ORF mammalian expression plasmid, C-HA tag||HG10573-CY|
|Human FGF10 Gene cDNA clone plasmid||HG10573-M|
|Human FGF10 ORF mammalian expression plasmid, N-Flag tag||HG10573-NF|
|Human FGF10 ORF mammalian expression plasmid, N-His tag||HG10573-NH|
|Human FGF10 ORF mammalian expression plasmid, N-Myc tag||HG10573-NM|
|Human FGF10 ORF mammalian expression plasmid, N-HA tag||HG10573-NY|
|Human FGF10 natural ORF mammalian expression plasmid||HG10573-UT|
|Learn more about expression Vectors|
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. FGF10 plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. FGF10 is required for normal branching morphogenesis. It may play a role in wound healing. Defects in FGF10 are the cause of autosomal dominant aplasia of lacrimal and salivary glands (ALSG). ALSG has variable expressivity, and affected individuals may have aplasia or hypoplasia of the lacrimal, parotid, submandibular and sublingual glands and absence of the lacrimal puncta. The disorder is characterized by irritable eyes, recurrent eye infections, epiphora (constant tearing) and xerostomia (dryness of the mouth), which increases the risk of dental erosion, dental caries, periodontal disease and oral infections.