|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.
|Human INHBA ORF mammalian expression plasmid, C-GFPSpark tag||HG10429-ACG|
|Human INHBA ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10429-ACR|
|Human INHBA ORF mammalian expression plasmid, C-Flag tag||HG10429-CF|
|Human INHBA ORF mammalian expression plasmid, C-His tag||HG10429-CH|
|Human INHBA ORF mammalian expression plasmid, C-Myc tag||HG10429-CM|
|Human INHBA ORF mammalian expression plasmid, C-HA tag||HG10429-CY|
|Human INHBA Gene cDNA clone plasmid||HG10429-M|
|Human INHBA ORF mammalian expression plasmid, N-Flag tag||HG10429-NF|
|Human INHBA ORF mammalian expression plasmid, N-His tag||HG10429-NH|
|Human INHBA ORF mammalian expression plasmid, N-Myc tag||HG10429-NM|
|Human INHBA ORF mammalian expression plasmid, N-HA tag||HG10429-NY|
|Human INHBA natural ORF mammalian expression plasmid||HG10429-UT|
|Learn more about expression Vectors|
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two monomers are linked to one another by a single disulfide bond. Activin is composed of two β subunits, βA βA (activin A), βB βB (activin B), or βA βB (activin AB). Inhibin is composed of an alpha and one of two β subunits, βA (inhibin A) or βB (inhibin B). Activins are produced in many cell types and organs, such as gonads, pituitary gland, and placenta. In the ovarian follicle, activin increases FSH binding and FSH-induced aromatization. It participates in androgen synthesis enhancing LH action in the ovary and testis. In the male, activin enhances spermatogenesis. In addition, Activin plays a role in wound repair and skin morphogenesis. Activin is strongly expressed in wounded skin, and overexpression of activin in epidermis of transgenic mice improves wound healing and enhances scar formation. Activin also regulates the morphogenesis of branching organs such as the prostate, lung, and kidney. There is also evidence showed that lack of activin during development results in neural developmental defects.