|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rhesus LAMP3 ORF mammalian expression plasmid, C-GFPSpark tag||CG90247-ACG|
|Rhesus LAMP3 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||CG90247-ACR|
|Rhesus LAMP3 ORF mammalian expression plasmid, C-Flag tag||CG90247-CF|
|Rhesus LAMP3 ORF mammalian expression plasmid, C-His tag||CG90247-CH|
|Rhesus LAMP3 ORF mammalian expression plasmid, C-Myc tag||CG90247-CM|
|Rhesus LAMP3 ORF mammalian expression plasmid, C-HA tag||CG90247-CY|
|Rhesus LAMP3 Gene cDNA clone plasmid||CG90247-G|
|Rhesus LAMP3 ORF mammalian expression plasmid, N-Flag tag||CG90247-NF|
|Rhesus LAMP3 ORF mammalian expression plasmid, N-His tag||CG90247-NH|
|Rhesus LAMP3 ORF mammalian expression plasmid, N-Myc tag||CG90247-NM|
|Rhesus LAMP3 ORF mammalian expression plasmid, N-HA tag||CG90247-NY|
|Rhesus LAMP3 natural ORF mammalian expression plasmid||CG90247-UT|
|Learn more about expression Vectors|
Dendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD208, also known as LAMP3, is a member of the lysosomal associated membrane protein (LAMP) family, which is specifically expressed by human dendritic cells (DCs) upon activation and therefore serves as marker of human DC maturation. Confocal and immunoelectron microscopy showed that mouse DC-LAMP protein co-localizes with lbm180, a specific marker for the limiting membrane of lamellar bodies that contain surfactant protein B. The present study demonstrates that DC-LAMP is constitutively expressed by mouse, sheep, and human type II pneumocytes. DC-LAMP is constitutively expressed in normal type II pneumocytes. DC-LAMP is detected first in activated human DC within MHC class II molecules-containing compartments just before the translocation of MHC class II-peptide complexes to the cell surface, suggesting a possible involvement in this process. Furthermore, overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces.