|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rhesus PPBP ORF mammalian expression plasmid, C-GFPSpark tag||CG90132-ACG|
|Rhesus PPBP ORF mammalian expression plasmid, C-OFPSpark / RFP tag||CG90132-ACR|
|Rhesus PPBP ORF mammalian expression plasmid, C-Flag tag||CG90132-CF|
|Rhesus PPBP ORF mammalian expression plasmid, C-His tag||CG90132-CH|
|Rhesus PPBP ORF mammalian expression plasmid, C-Myc tag||CG90132-CM|
|Rhesus PPBP ORF mammalian expression plasmid, C-HA tag||CG90132-CY|
|Rhesus PPBP Gene cDNA clone plasmid||CG90132-G|
|Rhesus PPBP ORF mammalian expression plasmid, N-Flag tag||CG90132-NF|
|Rhesus PPBP ORF mammalian expression plasmid, N-His tag||CG90132-NH|
|Rhesus PPBP ORF mammalian expression plasmid, N-Myc tag||CG90132-NM|
|Rhesus PPBP ORF mammalian expression plasmid, N-HA tag||CG90132-NY|
|Rhesus PPBP natural ORF mammalian expression plasmid||CG90132-UT|
|Learn more about expression Vectors|
Pro-platelet basic protein (PPBP) is also known as Chemokine (C-X-C motif) ligand 7 (CXCL7) and nucleosome assembly protein (Nap-2). Nap-2 / PPBP / CXCL7 is released in large amounts from platelets following their activation and is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. Nap-2 / PPBP / CXCL7 has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Nap-2 is a ligand for CXCR1 and CXCR2, and Nap-2, Nap-2 (73), Nap-2 (74), Nap-2 (1-66), and most potent Nap-2 (1-63) are chemoattractants and activators for neutrophils.