|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A myc tag can be used in many different assays that require recognition by an antibody. If there is no antibody against the studied protein, adding a myc-tag allows one to follow the protein with an antibody against the Myc epitope. Examples are cellular localization studies by immunofluorescence or detection by Western blotting.
The peptide sequence of the myc-tag is: N-EQKLISEEDL-C (1202 Da). It can be fused to the C-terminus and the N-terminus of a protein. It is advisable not to fuse the tag directly behind the signal peptide of a secretory protein, since it can interfere with translocation into the secretory pathway.
|Human LSAMP ORF mammalian expression plasmid, C-GFPSpark tag||HG12136-ACG|
|Human LSAMP ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG12136-ACR|
|Human LSAMP ORF mammalian expression plasmid, C-Flag tag||HG12136-CF|
|Human LSAMP ORF mammalian expression plasmid, C-His tag||HG12136-CH|
|Human LSAMP ORF mammalian expression plasmid, C-Myc tag||HG12136-CM|
|Human LSAMP ORF mammalian expression plasmid, C-HA tag||HG12136-CY|
|Human LSAMP Gene cDNA clone plasmid||HG12136-G|
|Human LSAMP ORF mammalian expression plasmid, N-Flag tag||HG12136-NF|
|Human LSAMP ORF mammalian expression plasmid, N-His tag||HG12136-NH|
|Human LSAMP ORF mammalian expression plasmid, N-Myc tag||HG12136-NM|
|Human LSAMP ORF mammalian expression plasmid, N-HA tag||HG12136-NY|
|Human LSAMP natural ORF mammalian expression plasmid||HG12136-UT|
|Learn more about expression Vectors|
The limbic system-associated membrane protein (LAMP) is a cell surface glycoprotein expressed by cortical and subcortical regions of the mammalian CNS that comprise or receive direct projections from limbic system structures. The 64-68-kDa glycoprotein limbic system-associated membrane protein (LsAMP) is expressed on the surface of somata and proximal dendrites of neurons. These areas perform cognitive and autonomic functions, also learning and memory. The functional analysis indicates that LsAMP acts as a selective adhesion molecule, serving as a guidance cue for specific patterns of connectivity, which underlies the normal development of the limbic system. In animal studies there have been found that rats with increased level of anxiety had 1.6-fold higher expression of LsAMP gene in the periaqueductal gray compared to rats with low level of anxiety, indicating a possible role of LsAMP in the regulation of anxiety.