|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive ,Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A myc tag is a polypeptide protein tag derived from the c-myc gene product that can be added to a protein using recombinant DNA technology. It can be used for affinity chromatography, then used to separate recombinant, overexpressed protein from wild type protein expressed by the host organism. It can also be used in the isolation of protein complexes with multiple subunits.
A myc tag can be used in many different assays that require recognition by an antibody. If there is no antibody against the studied protein, adding a myc-tag allows one to follow the protein with an antibody against the Myc epitope. Examples are cellular localization studies by immunofluorescence or detection by Western blotting.
The peptide sequence of the myc-tag is: N-EQKLISEEDL-C (1202 Da). It can be fused to the C-terminus and the N-terminus of a protein. It is advisable not to fuse the tag directly behind the signal peptide of a secretory protein, since it can interfere with translocation into the secretory pathway.
|Human LYZL2 ORF mammalian expression plasmid, C-GFPSpark tag||HG13726-ACG|
|Human LYZL2 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG13726-ACR|
|Human LYZL2 ORF mammalian expression plasmid, C-Flag tag||HG13726-CF|
|Human LYZL2 ORF mammalian expression plasmid, C-His tag||HG13726-CH|
|Human LYZL2 ORF mammalian expression plasmid, C-Myc tag||HG13726-CM|
|Human LYZL2 ORF mammalian expression plasmid, C-HA tag||HG13726-CY|
|Human LYZL2 Gene cDNA clone plasmid||HG13726-G|
|Human LYZL2 ORF mammalian expression plasmid, N-Flag tag||HG13726-NF|
|Human LYZL2 ORF mammalian expression plasmid, N-His tag||HG13726-NH|
|Human LYZL2 ORF mammalian expression plasmid, N-Myc tag||HG13726-NM|
|Human LYZL2 ORF mammalian expression plasmid, N-HA tag||HG13726-NY|
|Human LYZL2 natural ORF mammalian expression plasmid||HG13726-UT|
|Learn more about expression Vectors|
Lysozyme 2 gene is a member of a family of lysozyme-like genes. Lysozymes, especially C-type lysozymes, are well-recognized bacteriolytic factors widely distributed in the animal kingdom and play a mainly protective role in host defense. Lysozymes damage bacterial cell walls by catalyzing hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.
Lysozyme is part of the innate immune system. Reduced lysozyme levels have been associated with bronchopulmonary dysplasia in newborns. In certain cancers (especially myelomonocytic leukemia) excessive production of lysozyme by cancer cells can lead to toxic levels of lysozyme in the blood. High lysozyme blood levels can lead to kidney failure and low blood potassium, conditions that may improve or resolve with treatment of the primary malignancy.