|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive ,Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A myc tag is a polypeptide protein tag derived from the c-myc gene product that can be added to a protein using recombinant DNA technology. It can be used for affinity chromatography, then used to separate recombinant, overexpressed protein from wild type protein expressed by the host organism. It can also be used in the isolation of protein complexes with multiple subunits.
A myc tag can be used in many different assays that require recognition by an antibody. If there is no antibody against the studied protein, adding a myc-tag allows one to follow the protein with an antibody against the Myc epitope. Examples are cellular localization studies by immunofluorescence or detection by Western blotting.
The peptide sequence of the myc-tag is: N-EQKLISEEDL-C (1202 Da). It can be fused to the C-terminus and the N-terminus of a protein. It is advisable not to fuse the tag directly behind the signal peptide of a secretory protein, since it can interfere with translocation into the secretory pathway.
|Human APCS ORF mammalian expression plasmid, C-GFPSpark tag||HG13610-ACG|
|Human APCS ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG13610-ACR|
|Human APCS ORF mammalian expression plasmid, C-Flag tag||HG13610-CF|
|Human APCS ORF mammalian expression plasmid, C-His tag||HG13610-CH|
|Human APCS ORF mammalian expression plasmid, C-Myc tag||HG13610-CM|
|Human APCS ORF mammalian expression plasmid, C-HA tag||HG13610-CY|
|Human APCS Gene cDNA clone plasmid||HG13610-G|
|Human APCS ORF mammalian expression plasmid, N-Flag tag||HG13610-NF|
|Human APCS ORF mammalian expression plasmid, N-His tag||HG13610-NH|
|Human APCS ORF mammalian expression plasmid, N-Myc tag||HG13610-NM|
|Human APCS ORF mammalian expression plasmid, N-HA tag||HG13610-NY|
|Human APCS natural ORF mammalian expression plasmid||HG13610-UT|
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Serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a highly preserved plasma protein named for its ubiquitous presence in amyloid deposits. As a normal plasma protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". Serum amyloid P component represents another member of the pentraxin family, a highly conserved group of molecules that may play a role in innate immunity. SAP is a key negative regulator for innate immune responses to DNA and may be partly responsible for the insufficient immune responses after DNA vaccinations in humans. SAP suppression may be a novel strategy for improving efficacy of human DNA vaccines and requires further clinical investigations.