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LY86 / MD-1 Antibody (PE), Rabbit MAb

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Mouse LY86 Antibody Product Information
Immunogen:Recombinant Mouse MD-1 / LY86 protein (Catalog#50062-M08H)
Clone ID:416
Ig Type:Rabbit IgG
Concentration:10 μl/Test, 0.1 mg/ml
Formulation:Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Mouse MD-1 / LY86 (rM MD-1 / LY86; Catalog#50062-M08H; NP_034875.1; Met1-Ser162) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Mouse LY86 Antibody Usage Guide
Specificity:Mouse MD-1 / LY86
Application:FCM
Storage:This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Mouse LY86 Antibody FC Application Image
[Click to enlarge image]
Caption:
Analysis of LY86 expression on spleen lymphocytes.
LY86 / MD-1 Antibody (PE), Rabbit MAb, Flow cytometric
Other LY86 Antibody Products
MD1 / MMD-1 / LY86 Background

MD-1 and MD-2 are secretory glycoproteins that exist on the cell surface in complexes with transmembrane proteins. MD-1 is anchored by radioprotective 105 (RP105) which is a molecule containing leucine-rich repeats and is expressed on B cells, dentritic cells and macrophages, while MD-2 is associated with TLR4. MD-1 is required for efficient RP105 cell surface expression and function. It is indicated that the RP105/MD1 complex, in conjunction with TLR4, mediates the innate immune response to LPS in B cells, and also plays a role in protecting against apoptosis, B-cell proliferation, etc. Mouse MD-1 cDNA encodes a 162 amino acid precursor protein with a putative 19 aa signal peptide and two potential N-linked glycosylation sites. It shares 40% and 66% amino acid sequence identity with chicken and human MD-1 respectively. MD-1 is mainly expressed in spleen, and also detectable in liver, brain, thymus, and kidney.

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