|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive ,Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokarfyotic expression systems.
|Human CNTN3 ORF mammalian expression plasmid, C-GFPSpark tag||HG10174-ACG|
|Human CNTN3 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10174-ACR|
|Human CNTN3 ORF mammalian expression plasmid, C-Flag tag||HG10174-CF|
|Human CNTN3 ORF mammalian expression plasmid, C-His tag||HG10174-CH|
|Human CNTN3 ORF mammalian expression plasmid, C-Myc tag||HG10174-CM|
|Human CNTN3 ORF mammalian expression plasmid, C-HA tag||HG10174-CY|
|人 CNTN3 基因全长ORF克隆||HG10174-M|
|Human CNTN3 ORF mammalian expression plasmid, N-Flag tag||HG10174-NF|
|Human CNTN3 ORF mammalian expression plasmid, N-His tag||HG10174-NH|
|Human CNTN3 ORF mammalian expression plasmid, N-Myc tag||HG10174-NM|
|Human CNTN3 ORF mammalian expression plasmid, N-HA tag||HG10174-NY|
|Human CNTN3 natural ORF mammalian expression plasmid||HG10174-UT|
|Learn more about expression Vectors|
Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2(TAG-1), Contactin-3(BIG-1), BIG-2, Contactin-5(NB-2) and NB-3. Since their identification in the late 1980s, Contactin-1 and Contactin-2 have been studied extensively. Axonal expression and the neurite extension activity of Contactin-1 and Contactin-2 attracted researchers to study the function of these molecules in axon guidance during development. Contactin-1 and Contactin-2 have come to be known as the principal molecules in the function and maintenance of myelinated neurons. In contrast, the function of the other four members of this subgroup remained unknown until recently. Contactin-3, also known as CNTN3 ( BIG-1 in rat and PANG in mouse ), is a GPI-linked glycoprotein that is expressed on cerebellar Purkinje cells, amygdaloid and thalamic neurons and olfactory granule cells. In the brain, Contactin-3 is expressed in frontal lobe, occipital lobe, cerebellum and amygdala. Contactin-3 contains 4 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. Human Contactin-3 shares 92% aa identity with mouse Contactin-3.The exact function of Contactin-3 is unclear. Contactin-3 may mediate cell-cell interaction and may promote neurite outgrowth.