|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A myc tag can be used in many different assays that require recognition by an antibody. If there is no antibody against the studied protein, adding a myc-tag allows one to follow the protein with an antibody against the Myc epitope. Examples are cellular localization studies by immunofluorescence or detection by Western blotting.
The peptide sequence of the myc-tag is: N-EQKLISEEDL-C (1202 Da). It can be fused to the C-terminus and the N-terminus of a protein. It is advisable not to fuse the tag directly behind the signal peptide of a secretory protein, since it can interfere with translocation into the secretory pathway.
|Human RP2 ORF mammalian expression plasmid, C-GFPSpark tag||HG10637-ACG|
|Human RP2 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10637-ACR|
|Human RP2 ORF mammalian expression plasmid, C-Flag tag||HG10637-CF|
|Human RP2 ORF mammalian expression plasmid, C-His tag||HG10637-CH|
|Human RP2 ORF mammalian expression plasmid, C-Myc tag||HG10637-CM|
|Human RP2 ORF mammalian expression plasmid, C-HA tag||HG10637-CY|
|Human RP2 Gene cDNA clone plasmid||HG10637-M|
|Human RP2 ORF mammalian expression plasmid, N-Flag tag||HG10637-NF|
|Human RP2 ORF mammalian expression plasmid, N-His tag||HG10637-NH|
|Human RP2 ORF mammalian expression plasmid, N-Myc tag||HG10637-NM|
|Human RP2 ORF mammalian expression plasmid, N-HA tag||HG10637-NY|
|Human RP2 natural ORF mammalian expression plasmid||HG10637-UT|
|Learn more about expression Vectors|
XRP2, also known as Protein XRP2 and RP2, is a member of the TBCC (tubulin cofactor C) family and contains one C-CAP/cofactor C-like domain. This protein is encoded by the RP2 gene in humans. XRP2 stimulates the GTPase activity of tubulin, but does not enhance tubulin heterodimerization. XRP2 acts as guanine nucleotide dissociation inhibitor for ARL3. Defects in RP2 gene are the cause of retinitis pigmentosa type 2 (RP2), also known as X-linked retinitis pigmentosa 2 (XLRP-2). It leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.