|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive ,Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokarfyotic expression systems.
|Rhesus CSF1 ORF mammalian expression plasmid, C-GFPSpark tag||CG90029-ACG|
|Rhesus CSF1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||CG90029-ACR|
|Rhesus CSF1 ORF mammalian expression plasmid, C-Flag tag||CG90029-CF|
|Rhesus CSF1 ORF mammalian expression plasmid, C-His tag||CG90029-CH|
|Rhesus CSF1 ORF mammalian expression plasmid, C-Myc tag||CG90029-CM|
|Rhesus CSF1 ORF mammalian expression plasmid, C-HA tag||CG90029-CY|
|Rhesus CSF1 Gene cDNA clone plasmid||CG90029-G|
|Rhesus CSF1 ORF mammalian expression plasmid, N-Flag tag||CG90029-NF|
|Rhesus CSF1 ORF mammalian expression plasmid, N-His tag||CG90029-NH|
|Rhesus CSF1 ORF mammalian expression plasmid, N-Myc tag||CG90029-NM|
|Rhesus CSF1 ORF mammalian expression plasmid, N-HA tag||CG90029-NY|
|Rhesus CSF1 natural ORF mammalian expression plasmid||CG90029-UT|
|Learn more about expression Vectors|
Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. M-CSF/CSF-1 is known to facilitate monocyte survival, monocyte-to-macrophage conversion, and macrophage proliferation. M-CSF/CSF-1 is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. It binds to the Colony stimulating factor 1 receptor. M-CSF/CSF-1 may also be involved in development of the placenta. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage, but also by regulating endothelial cell chemokine expression.