|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A myc tag can be used in many different assays that require recognition by an antibody. If there is no antibody against the studied protein, adding a myc-tag allows one to follow the protein with an antibody against the Myc epitope. Examples are cellular localization studies by immunofluorescence or detection by Western blotting.
The peptide sequence of the myc-tag is: N-EQKLISEEDL-C (1202 Da). It can be fused to the C-terminus and the N-terminus of a protein. It is advisable not to fuse the tag directly behind the signal peptide of a secretory protein, since it can interfere with translocation into the secretory pathway.
|Canine IL20RA ORF mammalian expression plasmid, C-GFPSpark tag||DG70080-ACG|
|Canine IL20RA ORF mammalian expression plasmid, C-OFPSpark / RFP tag||DG70080-ACR|
|Canine IL20RA ORF mammalian expression plasmid, C-Flag tag||DG70080-CF|
|Canine IL20RA ORF mammalian expression plasmid, C-His tag||DG70080-CH|
|Canine IL20RA ORF mammalian expression plasmid, C-Myc tag||DG70080-CM|
|Canine IL20RA ORF mammalian expression plasmid, C-HA tag||DG70080-CY|
|Canine IL20RA Gene cDNA clone plasmid||DG70080-G|
|Canine IL20RA ORF mammalian expression plasmid, N-Flag tag||DG70080-NF|
|Canine IL20RA ORF mammalian expression plasmid, N-His tag||DG70080-NH|
|Canine IL20RA ORF mammalian expression plasmid, N-Myc tag||DG70080-NM|
|Canine IL20RA ORF mammalian expression plasmid, N-HA tag||DG70080-NY|
|Canine IL20RA natural ORF mammalian expression plasmid||DG70080-UT|
|Learn more about expression Vectors|
Interleukin 20 receptor, alpha subunit (IL20RA/IL-20RA) also known as IL-20 receptor subunit alpha, Cytokine receptor class-II member 8, interleukin-20 receptor I, and interleukin-20 receptor subunit alpha, is a subunit for the interleukin-20 receptor. IL20RA/IL-20RA belongs to the type II cytokine receptor family. This cytokine is a receptor for interleukin 20 (IL20), a cytokine that may be involved in epidermal function. The receptor of IL20 is a heterodimeric receptor complex consisting of this protein and interleukin 20 receptor beta (IL20B). IL20RA forms heterodimer with IL20RB, and the complex serves as a receptor for IL19, IL20 and IL24. All three are capable of signaling through IL-20RA/IL-20RB complex. The ligand binding to receptor B creating a high-affinity binding site for the receptor A which is recruited to complete the complex. In addition, IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26. IL20RA is widely expressed with highest levels in skin, testis and brain. The expression of both IL20RA and IL20RB is found to be upregulated in psoriatic skin lesions on keratinocytes.