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Mouse PGRL / IGSF8 Protein (Fc Tag)

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Mouse IGSF8 Protein Product Information
Synonym:AA033172, AU041109, ESTM34, EWI-2, KCT-4, PGRL, R75384
Protein Construction:A DNA sequence encoding the mouse IGSF8 (NP_536344.1) extracellulkar domain (Met 1-Thr 577) was fused with the Fc region of human IgG1 at the C-terminus.
Expressed Host:Human Cells
Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Mouse IGSF8 Protein QC Testing
Purity:> 90 % as determined by SDS-PAGE
Endotoxin:< 1.0 EU per μg of the protein as determined by the LAL method
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:Arg 26
Molecule Mass:The secreted recombinant mouse IGSF8/Fc is a disulfide-linked homodimer. The reduced monomer comprises 793 amino acids and has a calculated molecular mass of 85.8 kDa. The apparent molecular mass of the monomer is approximately 80 kDa in SDS-PAGE under reducing conditions.
Formulation:Lyophilized from sterile PBS, pH 7.4
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Mouse IGSF8 Protein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Mouse IGSF8 Protein SDS-PAGE
Mouse PGRL / IGSF8 Protein (Fc Tag) SDS-PAGE
Other IGSF8 Recombinant Protein Products
Mouse IGSF8 References
  • Glazar AI, et al. (2009) Immunoglobulin superfamily member IgSF8 (EWI-2) and CD9 in fertilisation: evidence of distinct functions for CD9 and a CD9-associated protein in mammalian sperm-egg interaction. Reprod Fertil Dev. 21(2): 293-303.
  • Murdoch JN, et al. (2003) Genomic organization and embryonic expression of Igsf8, an immunoglobulin superfamily member implicated in development of the nervous system and organ epithelia. Mol Cell Neurosci. 22(1): 62-74.
  • Zhang XA, et al. (2003) EWI2/PGRL associates with the metastasis suppressor KAI1/CD82 and inhibits the migration of prostate cancer cells. Cancer Res. 63 (10): 2665-74.
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    Catalog: 51042-M02H-20
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