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CD48 / SLAMF2 Antibody (FITC), Rabbit MAb

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Mouse CD48 Antibody Product Information
Immunogen:Recombinant Mouse CD48 protein (Catalog#50415-M08H)
Clone ID:341
Ig Type:Rabbit IgG
Concentration:10 μl/Test, 0.1 mg/ml
Formulation:Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD48 / SLAMF2 (rM CD48 / SLAMF2; Catalog#50415-M08H; NP_031675.1; Met 1-Arg 216) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Mouse CD48 Antibody Usage Guide
Specificity:Mouse CD48 / SLAMF2
Application:FCM
Storage:This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Mouse CD48 Antibody FC Application Image
[Click to enlarge image]
Caption:
Flow cytometric analysis of CD48 expression on spleen lymphocytes. BALB/c splenocytes were treated with Mouse BD Fc Block™ purified anti-CD16/CD32 mAb 2.4G2 (Cat. No. 553141) and stained with FITC-conjugated anti-Mouse CD48 (50415-R341-F). The histogram were derived from the gated events based on light scattering characteristics of lymphocytes.
CD48 / SLAMF2 Antibody (FITC), Rabbit MAb, Flow cytometric
Other CD48 Antibody Products
CD48/SLAMF2 Background

Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.

Mouse CD48/SLAMF2 References
  • Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50
  • Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"