|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Dffrx, Fam, Fgf-1, Fgfa, Fgf1|
|A DNA sequence encoding the mature form of mouse FGF1 (NP_034327.1) (Phe16-Asp155) was expressed. Mouse and Rat FGF1 sequences are identical.|
|In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.|
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
|> 90 % as determined by SDS-PAGE|
|Measured in a cell proliferation assay using BALB/c 3T3 mouse fibroblasts.|
The ED50 for this effect is typically 0.05-0.25 ng/mL in the presence of 10 μg/ml heparin.
|Please contact us for more information.|
|Samples are stable for up to twelve months from date of receipt at -70℃|
|The recombinant mouse FGF1 consisting of 141 amino acids and has a calculated molecular mass of 16 kDa as estimated in SDS-PAGE under reducing conditions.|
|Lyophilized from sterile 50mM Na2SO4, 0.5mM DTT, 1mM EDTA, 20mM Tris, pH 7.5|
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
|Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which results in receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer.