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MERS-CoV (NCoV / Novel coronavirus) Nucleocapsid Protein Antibody, Rabbit PAb, Antigen Affinity Purified

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MERS-CoV NP-CoV Antibody Product Information
Immunogen:Recombinant MERS-CoV (NCoV / Novel coronavirus) Nucleoprotein / NP protein (Catalog#40068-V08B)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:Produced in rabbits immunized with purified, recombinant MERS-CoV (NCoV / Novel coronavirus) Nucleoprotein / NP (Catalog#40068-V08B; AFS88943.1; Met 1-Asp413). Nucleoprotein specific IgG was purified by MERS-CoV (NCoV / Novel coronavirus) Nucleoprotein / NP affinity chromatography.
MERS-CoV NP-CoV Antibody Usage Guide
Specificity:The antibody reacts with MERS-CoV (NCoV / Novel coronavirus) Nucleocapsid protein (NP protein).
Application:WB, ELISA, IHC, IF, IP (Antibody's applications have not been validated with corresponding viruses. Optimal concentrations/dilutions should be determined by the end user.)

WB: 0.5-1 μg/mL

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect MERS-CoV (NCoV / Novel coronavirus) NP (Catalog# 40068-V08B) in ELISA.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
MERS-CoV NP-CoV Antibody WB Application Image
Anti-Novel coronavirus (HCoV-EMC/2012) Nucleocapsid Protein Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot
Anti-Novel coronavirus (HCoV-EMC/2012) Nucleocapsid Protein Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot
Other NP-CoV Antibody Products
CoV Nucleoprotein Background

Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronaviruses primarily cause respiratory and enteric diseases in mammals and birds. Coronaviruses can cause a range of symptoms varying from mild symptoms such as the common cold to more serious respiratory illnesses. They primarily cause respiratory and enteric diseases in mammals and birds. Coronavirus symptoms include rhinorrhea, sneezing, cough, nasal obstruction, bronchitis and so on. There are three main groups of coronaviruses: alpha, beta, and gamma. Proteins that contribute to the overall structure of all coronaviruses are the spike (S), envelope (E), membrane (M) and nucleoprotein (N). Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch.

MERS-CoV CoV Nucleoprotein References
  1. 1.Van Boheemen S, et al. (2012), MBio. 3(6):e00473-12.
  2. Bisht H. et al., 2004, Proc Natl Acad Sci. 101 (17): 6641-6.
  3. Li W. et al., 2005, Science. 309 (5742): 1864-8.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"