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Human CSNK2A2 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged

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CSNK2A2cDNA Clone Product Information
Gene_bank_ref_id:NM_001896.2
cDNA Size:1053
cDNA Description:ORF Clone of Homo sapiens casein kinase 2, alpha prime polypeptide DNA.
Gene Synonym:CK2A2, CSNK2A1, FLJ43934
Species:Human
Vector:pCMV3-untagged
Restriction Site:
Tag Sequence:
Sequence Description:
Shipping_carrier:Each tube contains approximately 10 μg of lyophilized plasmid.
Storage:The lyophilized plasmid can be stored at ambient temperature for three months.
pCMV3-untagged Vector Information
 
Vector Name pCMV3-untagged
Vector Size 6223bp
Vector Type Mammalian Expression Vector
Expression Method Constiutive ,Stable / Transient
Promoter CMV
Antibiotic Resistance Ampicillin
Selection In Mammalian Cells Hygromycin
Protein Tag None
Sequencing Primer Forward:T7(TAATACGACTCACTATAGGG)
Reverse:BGH(TAGAAGGCACAGTCGAGG)

pCMV3-untagged Physical Map

Schematic of pCMV3-untagged Multiple Cloning Sites
Human CSNK2A2 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged on other vectors
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Human CSNK2A2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-GFPSpark-taggedHG11018-ANG$325
Human CSNK2A2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-OFPSpark tagHG11018-ANR$325
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Human CSNK2A2 Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-taggedHG11018-CM$295
Human CSNK2A2 Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-taggedHG11018-CY$295
Human CSNK2A2 Gene cDNA Clone (full-length ORF Clone)HG11018-M$95
Human CSNK2A2 Gene cDNA Clone (full-length ORF Clone) expression ready, FLAG-taggedHG11018-M-F$295
Human CSNK2A2 Gene cDNA Clone (full-length ORF Clone) expression ready, untaggedHG11018-M-N$295
Human CSNK2A2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-taggedHG11018-NF$295
Human CSNK2A2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-taggedHG11018-NH$295
Human CSNK2A2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-taggedHG11018-NM$295
Human CSNK2A2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-taggedHG11018-NY$295
Human CSNK2A2 Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedHG11018-UT$295
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Background

Casein kinase II subunit alpha', also known as CSNK2A2 and CK2A2, is a member of the protein kinase superfamily, Ser/Thr protein kinase family and CK2 subfamily. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. CSNK2A2 is a tetramer composed of an alpha chain, an alpha' and two beta chains. It is also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation. Protein kinase casein kinase II (Ck2) is a cyclic-AMP and calcium-independent serine-threonine kinase that is composed of two catalytic subunits (alpha and alpha') and two regulatory beta-subunits. Ck2 is not a casein kinase in vivo, but over 100 substrates are known. The highly conserved amino acid sequences of its subunits and their broad expression suggest that Ck2 may have a fundamental role in cell function. Ck2 has been implicated in DNA replication, regulation of basal and inducible transcription, translation and control of metabolism. The Ck2alpha and Ck2alpha' isoforms (products of the genes Csnk2a1 and Csnk2a2, respectively) are highly homologous, the reason for their redundancy and evolutionary conservation is unknown. CSNK2A2 may be a candidate gene for these inherited syndromes.

References
  • Xu X. et al., 1999, Nat Genet. 23 (1):118-21.
  • Aasland M. et al., 2000, Anim Genet. 31 (2):131-4.
  • Escalier D. et al., 2003, Mol Reprod Dev. 66 (2):190-201.
  • Ackermann K. et al., 2005, Mol Cell Biochem. 274 (1-2):91-101.
  • Size / Price
    Catalog:HG11018-UT
    List Price: $295.00  (Save $0.00)
    Price:$295.00      [How to order]
    Availability2-3 weeks
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