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CD226 / DNAM-1 Antibody (APC), Rabbit MAb

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Mouse CD226 Antibody Product Information
Immunogen:Recombinant Mouse CD226 / DNAM-1 protein (Catalog#50232-M08H)
Clone ID:026
Ig Type:Rabbit IgG
Concentration:2 μl/Test, 0.1 mg/ml
Formulation:Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD226 / DNAM-1 (rM CD226 / DNAM-1; Catalog#50232-M08H; NP_848802.2; Met1-Pro254) and conjugated with APC under optimum conditions, the unreacted APC was removed.
Mouse CD226 Antibody Usage Guide
Specificity:Mouse CD226 / DNAM-1
Storage:This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Mouse CD226 Antibody FC Application Image
[Click to enlarge image]
Flow cytometric analysis of mouse CD226 expression on mouse splenocytes. BABL/c splenocytes were stained with FITC-conjugated anti-Mouse CD8a and APC-conjugated anti-Mouse CD226. The histogram were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
CD226 / DNAM-1 Antibody (APC), Rabbit MAb, Flow cytometric analysis
Other CD226 Antibody Products
CD226/DNAM-1 Background

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD226, also known as PTA1 or DNAM-1, is a member of the immunoglobulin superfamily containing 2 Ig-like domains of the V-set. High rate of CD226 (Cluster of Differentiation 226) is found on the surface of natural killer cells, platelets, monocytes and a subset of T cells. CD226 have binding sites with CD112 and CD155 and mediate cellular adhesion to other cells containing its ligands.

Mouse CD226/DNAM-1 References
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
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