|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Recombinant Human CCL24 / Eotaxin-2 / MPIF-2 protein (Catalog#10901-H08B)|
|0.2 μm filtered solution in PBS|
|Produced in rabbits immunized with purified, recombinant Human CCL24 / Eotaxin-2 / MPIF-2 (rh CCL24 / Eotaxin-2 / MPIF-2; Catalog#10901-H08B; O00175; Met1-Cys119). CCL24 / Eotaxin-2 / MPIF-2 specific IgG was purified by Human CCL24 / Eotaxin-2 / MPIF-2 affinity chromatography.|
|Human CCL24 / Eotaxin-2 / MPIF-2|
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human CCL24 / Eotaxin-2 / MPIF-2. The detection limit for Human CCL24 / Eotaxin-2 / MPIF-2 is < 0.039 ng/well.
|This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.|
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL24 displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. CCL24 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 is chemotactic for resting T-lymphocytes, and eosinophils. It has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. It is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Eotaxin-2 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils. Elevated level of Eotaxin-2 has been seen in patients with aspirin-exacerbated respiratory disease.