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CLEC5A / MDL1 / MDL-1 Antibody, Rabbit PAb, Antigen Affinity Purified

DatasheetSpecific ReferencesReviewsRelated ProductsProtocols
Rat CLEC5A Antibody Product Information
Immunogen:Recombinant Rat CLEC5A / MDL1 / MDL-1 protein (Catalog#80259-R07H)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS
Preparation:Produced in rabbits immunized with purified, recombinant Rat CLEC5A / MDL1 / MDL-1 (rh CLEC5A / MDL1 / MDL-1; Catalog#80259-R07H; F7GAV1; Val30-Lys190). CLEC5A / MDL1 / MDL-1 specific IgG was purified by Rat CLEC5A / MDL1 / MDL-1 affinity chromatography.
Rat CLEC5A Antibody Usage Guide
Specificity:Rat CLEC5A / MDL1 / MDL-1
Application:ELISA

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Rat CLEC5A / MDL1 / MDL-1. The detection limit for Rat CLEC5A / MDL1 / MDL-1 is < 0.039 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other CLEC5A Antibody Products
CLEC5A / MDL1 / MDL-1 Background

CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.

Rat CLEC5A / MDL1 / MDL-1 References
  • Chen ST. et al., 2008, Nature. 453 (7195): 672-6.
  • Davila S. et al., 2010, Genes Immun. 11 (3): 232-8.
  • Hillier LW. et al., 2003, Nature. 424 (6945): 157-64.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"