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CREB3L1 / OASIS Antibody, Rabbit PAb, Antigen Affinity Purified

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Human CREB3L1 Antibody Product Information
Immunogen:Recombinant Human CREB3L1 / OASIS protein (Catalog#12712-H08H)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS
Preparation:Produced in rabbits immunized with purified, recombinant Human CREB3L1 / OASIS (rh CREB3L1 / OASIS; Catalog#12712-H08H; Q96BA8-1; Glu396- Ser519). CREB3L1 / OASIS specific IgG was purified by Human CREB3L1 / OASIS affinity chromatography.
Human CREB3L1 Antibody Usage Guide
Specificity:Human CREB3L1 / OASIS
Application:ELISA

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human CREB3L1 / OASIS. The detection limit for Human CREB3L1 / OASIS is < 0.039 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other CREB3L1 Antibody Products
CREB3L1 / OASIS Background

CREB3L1, also known as OASIS, is a cellular transcription factor synthesized as a membrane-bound precursor. It is a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation. OASIS mRNA expression was detected in pancreatic β-cell lines and rodent islets, and the expression level was up-regulated by ER stress-inducing compounds. CREB3L1 may have a role in pancreas development. CREB3L1 may also play an important role in limiting virus spread by inhibiting proliferation of virus-infected cells. In vitro, CREB3L1 binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE. It may play a role in gliosis.

Human CREB3L1 / OASIS References
  • Denard B. et al., 2011, Cell Host Microbe. 10 (1): 65-74.
  • Debelenko LV. et al., 2011, 50 (12): 1054-62.
  • Vellanki. et al., 2010, Endocrinology. 151 (9): 4146.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"