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|Recombinant Human MKK6 / MEK6 / MAP2K6 protein (Catalog#10422-H20B1)|
|0.2 μm filtered solution in PBS|
|Produced in rabbits immunized with purified, recombinant Human MKK6 / MEK6 / MAP2K6 (rh MKK6 / MEK6 / MAP2K6; Catalog#10422-H20B1; P52564-1; Met1-Asp334,Ser207/Asp,211Thr/Asp). MKK6 / MEK6 / MAP2K6 specific IgG was purified by Human MKK6 / MEK6 / MAP2K6 affinity chromatography.|
|Human MKK6 / MEK6 / MAP2K6|
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human MKK6 / MEK6 / MAP2K6. The detection limit for Human MKK6 / MEK6 / MAP2K6 is < 0.039 ng/well.
|This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.|
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6 and MKK6, is a protein which belongs to the?protein kinase superfamily, STE Ser / Thr protein kinase family and MAP kinase kinase subfamily. MAP2K6 / MKK6 contains one?protein kinase domain. Mitogen-activated protein kinases are members of a conserved cascade of kinases involved in many signal transduction pathways. They stimulate phosphorylation of transcription factors in response to extracellular signals such as growth factors, cytokines, ultraviolet light, and stress-inducing agents. MAP2K6 / MKK6 exists in a variety of alternatively spliced isoforms with distinct patterns of tissue expression. Isoform 2 of MAP2K6 / MKK6 is only expressed in skeletal muscle. Isoform 1 of MAP2K6 / MKK6 is expressed in skeletal muscle, heart, and in lesser extent in liver or pancreas.