|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Recombinant Human BLOC1S2 / BLOS2 protein (Catalog#13916-H09E)|
|0.2 μm filtered solution in PBS|
|Produced in rabbits immunized with purified, recombinant Human BLOC1S2 / BLOS2 (rh BLOC1S2 / BLOS2; Catalog#13916-H09E; Q6QNY1-2; Met1-Arg99). BLOC1S2 / BLOS2 specific IgG was purified by Human BLOC1S2 / BLOS2 affinity chromatography.|
|Human BLOC1S2 / BLOS2|
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human BLOC1S2 / BLOS2. The detection limit for Human BLOC1S2 / BLOS2 is < 0.039 ng/well.
|This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.|
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
BLOC1S2, also known as BLOS2, belongs to the BLOC1S2 family. It is a component of BLOC-1 complex. The BLOC-1 complex is composed of BLOC1S1, BLOC1S2, BLOC1S3, DTNBP1, MUTED, PLDN, CNO/cappuccino and SNAPIN. The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. BLOC1S2 interacts directly with BLOC1S1, BLOC1S3, MUTED, CNO/cappuccino and SNAPIN. It may play a role in cell proliferation. It also plays a role in intracellular vesicle trafficking. Functionally, BLOC1S2 gene has been proposed to participate in processes (melanosome organization, microtubule nucleation, platelet dense granule organization, positive regulation of cell proliferation, positive regulation of transcription, regulation of apoptosis, positive regulation of transcription from RNA polymerase II promoter).