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FOP / FGFR1OP Antibody, Rabbit PAb, Antigen Affinity Purified

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Human FGFR1OP Antibody Product Information
Immunogen:Recombinant Human FOP / FGFR1OP protein (Catalog#14414-H20B)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS
Preparation:Produced in rabbits immunized with purified, recombinant Human FOP / FGFR1OP (rh FOP / FGFR1OP; Catalog#14414-H20B; FR1OP_HUMAN; Ala2-Ala379). FOP / FGFR1OP specific IgG was purified by Human FOP / FGFR1OP affinity chromatography.
Human FGFR1OP Antibody Usage Guide
Specificity:Human FOP / FGFR1OP
Application:ELISA

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human FOP / FGFR1OP. The detection limit for Human FOP / FGFR1OP is < 0.039 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other FGFR1OP Antibody Products
FOP / FGFR1OP Background

FOP( fibroblast growth factor receptor 1 oncogene partner) is a largely hydrophilic protein postulated to be a leucine-rich protein family member. FOP contains 1 LisH domain. A t(6;8)(q27;p11) chromosomal translocation, fusing FOP gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. FOP gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.

Human FOP / FGFR1OP References
  • Reither A. et al., 1999, Med Klin (Munich). 94 (4): 207-10.
  • Guasch G. et al., 2004, Blood. 103 (1): 309-12.
  • Popovici C. et al., 1999, Blood. 93 (4): 1381-9.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"