|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Recombinant Human FOP / FGFR1OP protein (Catalog#14414-H20B)|
|0.2 μm filtered solution in PBS|
|Produced in rabbits immunized with purified, recombinant Human FOP / FGFR1OP (rh FOP / FGFR1OP; Catalog#14414-H20B; FR1OP_HUMAN; Ala2-Ala379). FOP / FGFR1OP specific IgG was purified by Human FOP / FGFR1OP affinity chromatography.|
|Human FOP / FGFR1OP|
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human FOP / FGFR1OP. The detection limit for Human FOP / FGFR1OP is < 0.039 ng/well.
|This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.|
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
FOP( fibroblast growth factor receptor 1 oncogene partner) is a largely hydrophilic protein postulated to be a leucine-rich protein family member. FOP contains 1 LisH domain. A t(6;8)(q27;p11) chromosomal translocation, fusing FOP gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. FOP gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.