|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Recombinant Human ARL2BP / BART1 protein (Catalog#14357-H07E)|
|0.2 μm filtered solution in PBS|
|Produced in rabbits immunized with purified, recombinant Human ARL2BP / BART1 (rh ARL2BP / BART1; Catalog#14357-H07E; Q9Y2Y0-1; Met1-His163). ARL2BP / BART1 specific IgG was purified by Human ARL2BP / BART1 affinity chromatography.|
|Human ARL2BP / BART1|
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human ARL2BP / BART1. The detection limit for Human ARL2BP / BART1 is < 0.039 ng/well.
|This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.|
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. ARL2BP binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of ARL2BP or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. ARL2BP is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. ARL2BP, together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. ARL2BP may play a role as an effector of ARL2.