|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Recombinant Human AMIGO2 / AMIGO-2 / alivin 1 protein (Catalog#13735-H08H)|
|0.2 μm filtered solution in PBS|
|Produced in rabbits immunized with purified, recombinant Human AMIGO2 / AMIGO-2 / alivin 1 (rh AMIGO2 / AMIGO-2 / alivin 1; Catalog#13735-H08H; NP_862830.1; Met1-Thr398). AMIGO2 / AMIGO-2 / alivin 1 specific IgG was purified by Human AMIGO2 / AMIGO-2 / alivin 1 affinity chromatography.|
|Human AMIGO2 / AMIGO-2 / alivin 1|
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human AMIGO2 / AMIGO-2 / alivin 1. The detection limit for Human AMIGO2 / AMIGO-2 / alivin 1 is 0.00245 ng/well.
IHC-P: 0.1-2 μg/mL
|This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.|
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
AMIGO2 contains Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. It belongs to the immunoglobulin superfamily, AMIGO family. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. It is required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may also contribute to signal transduction through its intracellular domain. It may play a role in the tumorigenesis of a subset of gastric adenocarcinomas. AMIGO2 is highly expressed in breast, ovary, cervix, and uterus.