|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Recombinant Human TNFR1 / CD120a / TNFRSF1A protein (Catalog#10872-H08H)|
|0.2 μm filtered solution in PBS|
|Produced in rabbits immunized with purified, recombinant Human TNFR1 / CD120a / TNFRSF1A (rh TNFR1 / CD120a / TNFRSF1A; Catalog#10872-H08H; NP_001056.1; Met1-Thr211). TNFR1 / CD120a / TNFRSF1A specific IgG was purified by Human TNFR1 / CD120a / TNFRSF1A affinity chromatography.|
|Human TNFR1 / CD120a / TNFRSF1A|
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human TNFR1 / CD120a / TNFRSF1A. The detection limit for Human TNFR1 / CD120a / TNFRSF1A is 0.00245 ng/well.
|This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.|
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes.