|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Recombinant Mouse CLEC10A / MGL1 / CD301 protein (Catalog#50707-M07H)|
|0.2 μm filtered solution in PBS|
|Produced in rabbits immunized with purified, recombinant Mouse CLEC10A / MGL1 / CD301 (rh CLEC10A / MGL1 / CD301; Catalog#50707-M07H; NP_001191181.1; Gln58-Ser305). CLEC10A / MGL1 / CD301 specific IgG was purified by Mouse CLEC10A / MGL1 / CD301 affinity chromatography.|
|Mouse CLEC10A / MGL1 / CD301|
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse CLEC10A / MGL1 / CD301. The detection limit for Mouse CLEC10A / MGL1 / CD301 is 0.00245 ng/well.
|This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.|
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is a type II transmembrane glycoproteins and is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). There are 2 homologues: MGL1 and MGL2 (CD301a and CD301b) in mice. MGL1/CD301a induces both the production and secretion of interleukin (IL)-10. MGL1/CD301a plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria.