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Human CCL23 / MIP 3 Protein (His Tag)

DatasheetSpecific ReferencesReviewsRelated ProductsProtocols
CCL23Protein Product Information
Synonym:MIP3, MPIF1, SCYA23
Protein Construction:A DNA sequence encoding the human CCL23 (P55773.3) (Arg46-Asn120) was expressed with a polyhistidine tag at the C-terminus.
Species:Human
Expressed Host:Yeast
Form & Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
CCL23Protein QC Testing
Purity:> 90 % as determined by SDS-PAGE
Endotoxin:Please contact us for more information.
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:Arg 46
Molecule Mass:The recombinant human CCL23 consists 85 amino acids and predicts a molecular mass of 9.9 kDa.
Formulation:Lyophilized from sterile PBS, pH 7.4.
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
CCL23Protein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Background

CCL23, also known as MIP 3, is a small cytokine which belongs to the CC chemokine family. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. CCL23 is predominantly expressed in lung and liver tissue, but also can be detected in bone marrow and placenta. It displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. CCL23 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.

References
  • Poposki JA. et al., 2011, J Allergy Clin Immunol. 128 (1): 73-81.
  • Matsumoto K. et al., 2011, Int Arch Allergy Immunol. 155 (1): 34-9.
  • Kim CS. et al., 2011, Inflamm Res. 60 (9): 889-95.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"