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Human SARS Coronavirus Nucleoprotein / NP Antibody, Rabbit PAb

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NP-CoVAntibody Product Information
Immunogen:Recombinant Human SARS Coronavirus Nucleoprotein / NP Protein (Catalog#40143-V08B)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Formulation:0.2 μm filtered solution in PBS
Preparation:Produced in rabbits immunized with purified, recombinant Human SARS Coronavirus Nucleoprotein / NP (rh NP-CoV; Catalog#40143-V08B; NP_828858.1; Met1-Ala422). Total IgG was purified by Protein A affinity chromatography.
NP-CoVAntibody Usage Guide
Specificity:Human SARS Coronavirus Nucleoprotein / NP
Application:ELISA

ELISA: 0.5-1.0 μg/mL

This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human SARS Coronavirus Nucleoprotein / NP. The detection limit for Human SARS Coronavirus Nucleoprotein / NP is 0.039 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Background

Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronaviruses primarily cause respiratory and enteric diseases in mammals and birds. Coronaviruses can cause a range of symptoms varying from mild symptoms such as the common cold to more serious respiratory illnesses. They primarily cause respiratory and enteric diseases in mammals and birds. Coronavirus symptoms include rhinorrhea, sneezing, cough, nasal obstruction, bronchitis and so on. There are three main groups of coronaviruses: alpha, beta, and gamma. Proteins that contribute to the overall structure of all coronaviruses are the spike (S), envelope (E), membrane (M) and nucleoprotein (N). Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch.

References
  1. 1.Van Boheemen S, et al. (2012), MBio. 3(6):e00473-12.
  2. Bisht H. et al., 2004, Proc Natl Acad Sci. 101 (17): 6641-6.
  3. Li W. et al., 2005, Science. 309 (5742): 1864-8.
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Catalog:40143-RP01-200
List Price: $230.00  (Save $0.00)
Price:$230.00      [How to order]
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