|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Recombinant Human GPD1 / Glycerolphosphate Dehydrogenase 1 protein (Catalog#15489-H07E)|
|0.2 μm filtered solution in PBS|
|Produced in rabbits immunized with purified, recombinant Human GPD1 / Glycerolphosphate Dehydrogenase 1 (rh GPD1; Catalog#15489-H07E; P21695; Met1-Met349). Total IgG was purified by Protein A affinity chromatography.|
|Human GPD1 / Glycerolphosphate Dehydrogenase 1|
ELISA: 0.5-1.0 μg/mL
This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human GPD1 / Glycerolphosphate Dehydrogenase 1. The detection limit for Human GPD1 / Glycerolphosphate Dehydrogenase 1 is 0.039 ng/well.
|This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.|
GPD1, also known as glycerolphosphate dehydrogenase 1, is a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. GPD1 catalyzes the reversible redox conversion of dihydroxyacetone phosphate (DHAP), thus plays a critical role in carbohydrate and lipid metabolism. It also reduces nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. Meanwhile, GPD1 and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in GPD1 gene are a cause of transient infantile hypertriglyceridemia.