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Human PFN4 / Profilin 4 Protein (His Tag)

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PFN4Protein Product Information
Synonym:PFN4
Protein Construction:A DNA sequence encoding the human PFN4 (NP_955378.1) (Met1-Ser129) was expressed with a polyhistide tag at the N-terminus.
Species:Human
Expressed Host:E. coli
Form & Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
PFN4Protein QC Testing
Purity:> 95 % as determined by SDS-PAGE
Endotoxin:Please contact us for more information.
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:His
Molecule Mass:The recombinant human PFN4 consists of 144 amino acids and predicts a molecular mass of 16.2 KDa. It migrates as an approximately 14 KDa band in SDS-PAGE under reducing conditions.
Formulation:Lyophilized from sterile PBS, 200mM Arg, pH 7.4.
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
PFN4Protein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
15093-H07E
Background

PFN4, also known as profilin 4, is a member of the profilin family. Profilin can be detected in all eukaryotic organisms. It plays an important role in the spatially and temporally controlled growth of actin microfilaments. Profilin is one of the most abundant actin monomer binders, but proteins such as CAP and (in mammals) thymosin β4 have some functional overlaps with profilin. In contrast, ADF/cofilin has some properties that antagonize profilin action. PFN4 also functions in the dynamic turnover and restructuring of the actin cytoskeleton.

References
  • Di Nardo A. et al., 2000, J Cell Sci. 113 (21): 3795-803.
  • Witke W. et al., 1998, EMBO J. 17 (4): 967-76.
  • Carlsson L. et al., 1977, J Mol Biol. 115 (3): 465-83.
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    Catalog:15093-H07E-20
    List Price: $108.00  (Save $0.00)
    Price:$108.00      [How to order]
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    • Human PFN4 / Profilin 4 Protein (His Tag) SDS-PAGE
    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"