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Human VAMP3 / Cellubrevin Protein (His Tag)

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Human VAMP3 Protein Product Information
Synonym:VAMP3, SYB3
Protein Construction:A DNA sequence encoding the human VAMP3 (Q15836) (Met1-Lys77) was expressed with a polyhistidine tag at the N-terminus.
Expressed Host:E. coli
Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Human VAMP3 Protein QC Testing
Purity:> 95 % as determined by SDS-PAGE
Endotoxin:Please contact us for more information.
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:His
Molecule Mass:The recombinant human VAMP3 consists of 92 amino acids and predicts a molecular mass of 10.6 KDa. It migrates as an approximately 11 KDa band in SDS-PAGE under reducing conditions.
Formulation:Lyophilized from sterile PBS, 10% Glycerol, pH 7.4.
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Human VAMP3 Protein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Human VAMP3 Protein SDS-PAGE
Human VAMP3 / Cellubrevin Protein (His Tag) SDS-PAGE
Other VAMP3 Recombinant Protein Products
VAMP3 / Cellubrevin Background

VAMP3, also known as cellubrevin, is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. Because of VAMP3 gene's high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, VAMP3 was shown to be the human equivalent of the rodent cellubrevin. In platelets VAMP3 resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.

Human VAMP3 / Cellubrevin References
  • Bernstein AM. et al., 1999, Blood. 93 (2): 571-9.
  • Annaert WG. et al., 1997, J Cell Biol. 139 (6): 1397-410.
  • Hager HA. et al., 2010, EMBO J. 29 (3): 532-45.
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    Catalog: 14481-H07E-20
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    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.