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Human CFHR2 / FHR2 / HFL3 Protein (His Tag)

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Human CFHR2 Protein Product Information
Protein Construction:A DNA sequence encoding the human CFHR2 (P36980-1) (Met1-Lys270) was expressed with a polyhistidine tag at the C-terminus.
Expressed Host:Human Cells
Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Human CFHR2 Protein QC Testing
Purity:> (46.1+45.6) % as determined by SDS-PAGE
Endotoxin:< 1.0 EU per μg of the protein as determined by the LAL method
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:Glu 19
Molecule Mass:The recombinant human CFHR2 consists of 263 amino acids and predicts a molecular mass of 30.2 KDa. It migrates as an approximately 31 and 35 KDa band in SDS-PAGE under reducing conditions.
Formulation:Lyophilized from sterile PBS, pH 7.4
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Human CFHR2 Protein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Human CFHR2 Protein SDS-PAGE
Human CFHR2 / FHR2 / HFL3 Protein (His Tag) SDS-PAGE
Other CFHR2 Recombinant Protein Products
CFHR2  Background

CFHR2 belongs to the complement factor H protein family. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 contains 4 Sushi (CCP/SCR) domains and is expressed by the liver and secreted in plasma. CFHR2 might be involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism.

Human CFHR2  References
  • Skerka C, et al. (1991) Molecular cloning of a human serum protein structurally related to complement factor H. J Biol Chem. 266(18):12015-20.
  • Daz-Guilln MA, et al. (1999) A radiation hybrid map of complement factor H and factor H-related genes. Immunogenetics. 49(6):549-52.
  • Strausberg RL, et al. (2003) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci. 99(26):16899-903.
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    Catalog: 13920-H08H-20
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