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Human COL5A2 Protein (Fc Tag)

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Human COL5A2 Protein Product Information
Protein Construction:A DNA sequence encoding the human COL5A2(P05997)(Met1-Leu1229) was fused with Fc region of mouse IgG at the C-terminus.
Expressed Host:Human Cells
Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Human COL5A2 Protein QC Testing
Purity:(26.7+59.2) % as determined by SDS-PAGE
Endotoxin:< 1.0 EU per μg of the protein as determined by the LAL method
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:Gln 27
Molecule Mass:The recombinant human COL5A2/mFc is a disulfide-linked homodimer. The reduced monomer comprises 1437 amino acids and has a predicted molecular mass of 138.6 kDa. The apparent molecular mass of the protein is approximately 75 and 60 in SDS-PAGE under reducing conditions.
Formulation:Lyophilized from sterile PBS, pH 7.4.
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Human COL5A2 Protein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Human COL5A2 Protein SDS-PAGE
Human COL5A2 Protein (Fc Tag) SDS-PAGE
Other COL5A2 Recombinant Protein Products
COL5A2 Background

COL5A2 is a component of type V collagen. It is known as the pro-alpha2(V) chain. COL5A2, together with two pro-alpha1(V) chains can form type V procollagen. These triple-stranded, rope-like procollagen molecules arrange themselves into long, thin fibrils that cross-link to one another in the spaces around cells. The cross-links result in the formation of very strong, mature type V collagen fibers. Type V collagen can be detected in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen.

Human COL5A2 References
  • Greenspan DS. et al., 1992, Genomics. 12 (4): 836-7.
  • Mann K. 1992, Biol Chem Hoppe-Seyler. 373 (2): 69-75.
  • Greenspan DS. et al., 1992, Gene Expr. 1 (1): 29-39.
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    Catalog: 13685-H05H-100
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